Hemophilia :: essays research papers

HemophiliaHemophilia is a componenttic blood disease, which is characterized by theinability of blood to clot, or change state even from minor injuries. This diseaseis caused by an insufficiency of certain blood proteins, called factors, thatparticipate in blood clotting and often by sudden gene mutation. Therefore,with the absence of factors, the blood clotting process is prolonged. There aredifferent types of hemophilia, hemophilia A and hemophilia B for example.Hemophilia A , the most third estate form is caused by the lack of factor VIII. Inthe second most parkland form of hemophilia, hemophilia B (also known as Christmasdisease), factor IX is absent.The condition appears when the person is born. Also, the disease ishereditary, passed on from parent to child. Because of its genetic makeup,hemophilia is carried by females however those affected are almost always males.In trinity of all cases hemophilia thought to be caused by spontaneous genemutation with no family history. T his is how females are able to be affectedby hemophilia. hereditary pattern is controlled by a recessive sex-linked factorcarried by the mother on the X chromosome. There is a fifty percent chance thatthe sons of a female carrier will have hemophilia. There also is a fiftypercent chance that the daughters of a female carrier will be carriers ofhemophilia. In addition, all daughters of men with hemophilia are carriers, buthis sons are unaffected. Men cannot transmit hemophilia, and female carriersare free of the disease.Hemophilia is the most common hereditary blood disorder. Currently,approximately one in every 10,000 people in all parts of the world suffers fromhemophilia. This blood related disease affects almost 20,000 people in the